Hillstream BioPharma is a development-stage company advancing improved therapies for patients with cancer.

Hillstream's competitive advantage is to enhance the safety and efficacy of oncology therapies by encapsulating them in a polymeric injectable suspension comprised of FDA-recognized inactive ingredients. Encapsulation ensures delivery within the tumor cells and prevents free drug levels in circulation that can cause toxicity. The slow and sustained release of the therapy may also reduce the frequency of dosing while maintaining its efficacy. The novel formulation allows Hillstream to build a strong patent estate and seek FDA Orphan Designation in specific indications.

Hillstream's formulations of tumor necrosis factor-alpha, salinomycin, bortezomib and paclitaxel are currently in preclinical development for cancers with significant unmet need. By taking advantage of the FDA's 505(b)(2) regulatory pathway for bortezomib and paclitaxel, the Company could expedite the development process and bring these novel formulations to market to offer patients hope.